GENETIC STUDIES ON ECTOPIA LENTIS*: II. ANTHROPOMETRIC AND LINKAGE DATA

Some Observations on Ectopia Lentis

Ectopia lentis et pupillae: the genetic aspects and differential diagnosis.

Two sib pairs and a fifth child are described with autosomal recessive ectopia lentis et pupillae. Patients with this disorder need regular ophthalmic review, but do not have the skeletal and metabolic complications associated with other syndromes with ectopia lentis.

Ectopia lentis et pupillae

The Ectopia lentis et pupillae is a rare genetic syndrome, congenital, autosomal recessive with variable expression, characterized by ectopia of the lens and the pupil, usually bilateral and symmetrical, but without systemic manifestations. The pathogenesis of this anomaly is still unknown, but there are theories that the change is mesodermal, neuroectodermal, combined or mechanical. This artic...

Familial ectopia lentis and its complications.

FAMILIAL ectopia lentis is a well recognized condition and is usually seen by the ophthalmologist in its fully developed stage. It was thought worth while to record this family, as some of the very earliest stages have been observed and the complications of the condition have been very varied. The family is a large one, spread over a large part of the Union of South Africa, and it has not been ...

Management of ectopia lentis in children.

Marfan syndrome, homocystinuria, trauma, and simple ectopia lentis are the most common causes of pediatric lens subluxation. Many patients are best treated with a careful refraction of the phakic or aphakic pupillary axis. For those patients not achieving satisfactory refractive results, endocapsular lensectomy using modern automated vitreous cutting devices is relatively safe and successful. G...